Figure 3.

(A) Schematic of the KOMP Regeneron-targeted mutation Glp2r^{tm1(KOMP)Vlcg} allele, based on the information posted at www.komp.org. (B) Glp2r expression in jejunum (Jej) and urinary bladder (UB) of WT Glp2r^+/+ (+/+), heterozygous Glp2r^+/Z (+/Z), and homozygous Glp2r^Z/Z (Z/Z) mice. Glp2r transcript abundance is expressed relative to the levels of Ppia mRNA, which were not statistically different between tissues. Shown are individual data points with overlapping means ± SD (n = 11 +/+, 10 +/Z, and 5 Z/Z mice). hUbCpro, promoter of the human ubiquitin C gene; loxP, loxP sites; neo^r, coding sequence of the neomycin phosphotransferase; p(A), polyadenylation signal; TM-LacZ, transmembrane domain-LacZ coding fusion protein.