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. 2019 Feb 12;24(6):e391–e393. doi: 10.1634/theoncologist.2018-0517

Figure 2.

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Representative genotyping results for 1 of the 8 informative markers (D13S158) demonstrating that the genotype of the tumor in the transplanted liver is the same as that of the donor. A panel of DNA markers that recognize highly variable regions of human DNA was used in a polymerase chain reaction‐based assay to compare DNA isolated from the liver tissue of the donor with the tumor and liver tissue of the recipient. The 12 markers tested were D7S484, D13S158, D10S197, D14S70, MYC1, D21S1252, D8S262, D17S250, D15S1002, D16S520, D2S2368, and DS6441. Eight of the 12 markers gave satisfactory results, and for those markers, 8 of the 8 genotypes of the newly diagnosed carcinoma matched those of the donor allograft tissue, whereas only 1 of the 8 genotypes of the carcinoma matched those of the patient's native liver.