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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: JAMA Cardiol. 2018 Aug 1;3(8):739–748. doi: 10.1001/jamacardio.2018.1511

Table 2.

Racial Differences in Patient Beliefs about Statins, Cholesterol, and Heart Disease in African American vs. Caucasian Adultsa

Survey Question Overall (n=5689) Primary Prevention (n=2482) Secondary Prevention (n=3207)
African
American
Caucasian p-value African
American
Caucasian p-value African
American
Caucasian p-value

Worry about disease and cholesterolb
 How often do you think or worry that you may have a heart attack or stroke? (%) 0.005 0.23 0.001
 Often 90 (13.4%) 433 (9.4%) 32 (9.0%) 123 (6.5%) 58 (18.4%) 310 (11.5%)
 Occasionally 195 (29.1%) 1,341 (29.2%) 104 (29.3%) 571 (30.2%) 91 (28.8%) 770 (28.6%)
 Rarely or never 386 (57.5%) 2,811 (61.3%) 219 (61.7%) 1,195 (63.3%) 167 (52.8%) 1,616 (59.9%)
 How do you think your risk of heart attack or stroke compares with other men/women your age? (% slightly higher to much worse) 213 (28.6%) 1,735 (36.2%) <0.001 99 (25.0%) 618 (31.0%) 0.009 114 (32.7%) 1,117 (39.9%) 0.02
 People with high cholesterol are more likely to have a heart attack 623 (77.3%) 3,954 (81.0%) 0.02 360 (80.0%) 1,640 (80.7%) 0.73 263 (73.9%) 2,314 (81.2%) 0.001
 People don’t need to worry about their cholesterol if they have never had a heart attack or other heart problem. 71 (8.8%) 404 (8.3%) 0.61 41 (9.1%) 154 (7.6%) 0.27 30 (8.4%) 250 (8.8%) 0.83
Statin efficacy
 Statin medications are effective in reducing the risk of heart disease and stroke 564 (70.0%) 3,635 (74.4%) 0.008 311 (69.1%) 1,441 (70.9%) 0.45 253 (71.1%) 2,194 (77.0%) 0.01
Statin safety
 Statins are safe medications 292 (36.2%) 2,800 (57.3%) <0.001 145 (32.2%) 1,112 (54.7%) <0.001 147 (41.3%) 1,688 (59.2%) <0.001
 I think statins can cause diabetes 61 (7.6%) 299 (6.1%) 0.12 26 (5.8%) 120 (5.9%) 0.92 35 (9.8%) 179 (6.3%) 0.01
 I think statins can cause muscle aches or pain 216 (26.8%) 1,913 (39.2%) <0.001 96 (21.3%) 728 (35.8%) <0.001 120 (33.7%) 1,185 (41.6%) 0.004
 I think statins can cause liver damage 157 (19.5%) 1,406 (28.8%) <0.001 67 (14.9%) 568 (28.0%) <0.001 90 (25.3%) 838 (29.4%) 0.11
 I think statins can cause memory loss 101 (12.5%) 558 (11.4%) 0.36 47 (10.4%) 206 (10.1%) 0.85 54 (15.2%) 352 (12.3%) 0.13
Clinician trust
 How much would you say you trust your doctors’ decisions about your medical care? (% generally trust or completely trust) 663 (87.0%) 4,579 (94.7%) <0.001 352 (85.2%) 1,906 (94.7%) <0.001 311 (89.1%) 2,673 (94.7%) <0.001
a

Statin-related beliefs and perceptions are presented here for African Americans vs. Caucasians, categorized by worries about disease, beliefs about efficacy, beliefs about safety, clinician trust and side effect experiences.

b

Responses presented are collected from patient survey questions asked on a five point Likert scale from strongly disagree to strongly agree, results shown are the % of participants who reported agree to strongly agree