Uniaxial stress test of wild-type (WT) and triple-knockout (TKO) pig pericardium (n = 3/group).
(A) Pericardium was harvested from 6 WT and 6 TKO pigs and tested for stress strain.
(B) Box plot of the maximum stress (10.56±4.39 MPa and 13.54 ± 2.61 MPa for the WT and TKO, respectively).
(C) Box plot of the strain at the maximum stress (WT was 74.62±12.43%, TKO was 67.81±6.44%).
(NS = not significant; TKO = triple-knockout (GTKO/β4GalNT2-KO/CMAHKO); WT = wild-type) (Reproduced from Zhang and colleagues [37] with permission from Elsevier)