FIGURE 3.

Transcriptomic metrics derived from S63 focused on inflammation, adaptive immunity, and endothelial activation. Individual metrics derived from subsets of genes involved in inflammation, endothelial activation, and adaptive immunity (S Table 2, http://links.lww.com/SLA/B564) were calculated in the 3 discrete outcomes. All values from trauma patients at <12 and 24 h were significantly greater than seen in healthy controls (^†††). For endothelial activation and inflammation, 24 h metrics were significantly lower than <12 h (P < 0.05 by paired- t test). (*P < 0.05; ^** P < 0.01 vs complicated outcome).