Table 3.
The univariate and multivariable models of all-cause mortality risk of different vascular access type on hemodialysis patients.
Variable | Classification | Univariate analysis | Multivariable analysis (1) | Multivariable analysis (2) | |||
---|---|---|---|---|---|---|---|
HR (95% CI) | p-valve | HR (95% CI) | p-valve | HR (95% CI) | p-valve | ||
Initial vascular access | Catheter vs. AVF/AVG | 1.73 (1.23, 2.45) | 0.0018 | 1.55 (1.09, 2.21) | 0.0150 | — | — |
Vascular Access type | AVF/AVG + catheter vs. AVF/AVG only | 1.80 (1.38, 2.34) | <0.0001 | — | — | 1.45 (1.11, 1.91) | <0.0001 |
Catheter only vs. AVF/AVG only | 3.79 (2.20, 6.52) | — | — | 3.23 (1.85, 5.64) | |||
Age | 1.06 (1.05, 1.08) | <0.0001 | 1.06 (1.05, 1.08) | <0.0001 | 1.06 (1.05, 1.07) | <0.0001 | |
Gender | Male/Female | 0.98 (0.76, 1.26) | 0.8555 | 1.24 (0.96, 1.60) | 0.1024 | 1.28 (0.99, 1.66) | 0.0588 |
FPG (mg/dl) | 126/<126 | 1.93 (1.50, 2.49) | <0.0001 | 1.77 (1.37, 2.29) | <0.0001 | 1.66 (1.28, 2.16) | 0.0001 |
Albumin (g/dl) | <3.5/3.5 | 1.77 (1.36, 2.32) | <0.0001 | 1.40 (1.06, 1.85) | 0.0166 | 1.42 (1.08, 1.88) | 0.0123 |
hsCRP (mg/L) | 4/<4 | 1.84 (1.41, 2.39) | <0.0001 | 1.48 (1.13, 1.93) | 0.0041 | 1.43 (1.09, 1.87) | 0.0094 |
Cholesterol (mg/dl) | 240/<240 | 1.17 (0.69, 1.97) | 0.5609 | — | — | ||
Triglyceride (mg/dl) | 200/<200 | 1.42 (1.09, 1.85) | 0.0096 | — | — | ||
Uric acid (mg/dl) | 8/<8 | 1.12 (0.93, 1.34) | 0.2291 | — | — | ||
AST (IU/L) | 40/<40 | 2.49 (1.59, 3.90) | <0.0001 | 2.69 (1.71, 4.23) | <0.0001 | 2.66 (1.68, 4.19) | <0.0001 |
ALT (IU/L) | 40/<40 | 1.52 (0.95, 2.44) | 0.0790 | — | — | ||
URR (%) | <65%/65% | 1.08 (0.96, 1.21) | 0.2178 | — | — | ||
Hb (g/dL) | <8.5/8.5 | 0.82 (0.61, 1.10) | 0.1824 | — | — | ||
Hct (%) | <28/28 | 0.78 (0.61, 1.01) | 0.0632 | — | — |
AVF: arteriovenous fistula; AVG: arteriovenous graft; URR: Urea reduction ratio; FPG: fasting plasma glucose; AST: aspartate aminotransferase; ALT: alanine aminotransferase; hsCRP: high-sensitivity C-reaction protein; Hb: hemoglobin; Hct: hematocrit.
NK: not known
Multivariable analysis (1): model for the initial use of vascular access type.
Multivariable analysis (2): model for the vascular access use in observed life-time.