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. 2019 Jul 24;9:10708. doi: 10.1038/s41598-019-47065-z

Table 3.

The univariate and multivariable models of all-cause mortality risk of different vascular access type on hemodialysis patients.

Variable Classification Univariate analysis Multivariable analysis (1) Multivariable analysis (2)
HR (95% CI) p-valve HR (95% CI) p-valve HR (95% CI) p-valve
Initial vascular access Catheter vs. AVF/AVG 1.73 (1.23, 2.45) 0.0018 1.55 (1.09, 2.21) 0.0150
Vascular Access type AVF/AVG + catheter vs. AVF/AVG only 1.80 (1.38, 2.34) <0.0001 1.45 (1.11, 1.91) <0.0001
Catheter only vs. AVF/AVG only 3.79 (2.20, 6.52) 3.23 (1.85, 5.64)
Age 1.06 (1.05, 1.08) <0.0001 1.06 (1.05, 1.08) <0.0001 1.06 (1.05, 1.07) <0.0001
Gender Male/Female 0.98 (0.76, 1.26) 0.8555 1.24 (0.96, 1.60) 0.1024 1.28 (0.99, 1.66) 0.0588
FPG (mg/dl) 126/<126 1.93 (1.50, 2.49) <0.0001 1.77 (1.37, 2.29) <0.0001 1.66 (1.28, 2.16) 0.0001
Albumin (g/dl) <3.5/3.5 1.77 (1.36, 2.32) <0.0001 1.40 (1.06, 1.85) 0.0166 1.42 (1.08, 1.88) 0.0123
hsCRP (mg/L) 4/<4 1.84 (1.41, 2.39) <0.0001 1.48 (1.13, 1.93) 0.0041 1.43 (1.09, 1.87) 0.0094
Cholesterol (mg/dl) 240/<240 1.17 (0.69, 1.97) 0.5609
Triglyceride (mg/dl) 200/<200 1.42 (1.09, 1.85) 0.0096
Uric acid (mg/dl) 8/<8 1.12 (0.93, 1.34) 0.2291
AST (IU/L) 40/<40 2.49 (1.59, 3.90) <0.0001 2.69 (1.71, 4.23) <0.0001 2.66 (1.68, 4.19) <0.0001
ALT (IU/L) 40/<40 1.52 (0.95, 2.44) 0.0790
URR (%) <65%/65% 1.08 (0.96, 1.21) 0.2178
Hb (g/dL) <8.5/8.5 0.82 (0.61, 1.10) 0.1824
Hct (%) <28/28 0.78 (0.61, 1.01) 0.0632

AVF: arteriovenous fistula; AVG: arteriovenous graft; URR: Urea reduction ratio; FPG: fasting plasma glucose; AST: aspartate aminotransferase; ALT: alanine aminotransferase; hsCRP: high-sensitivity C-reaction protein; Hb: hemoglobin; Hct: hematocrit.

NK: not known

 Multivariable analysis (1): model for the initial use of vascular access type.

Multivariable analysis (2): model for the vascular access use in observed life-time.