. 2019 May 15;81(7):949–957. doi: 10.1292/jvms.19-0012

Table 4. Least square mean (95% CI) obtained from linear mixed model for LA phasic function variables derived from 2D-STE before (baseline) and each times point during acute volume loading in 6 healthy beagles.

Variables		Baseline	15 min	30 min	45 min	60 min	75 min	90 min
Vmin		6.12 (4.47–7.77)	6.91 (5.24–8.58)	7.93 (6.29–9.58)	6.66 (5.01–8.30)	7.44 (5.79–9.09)	8.52 (6.87–10.17)^a)	8.76 (7.11–10.41)^a)
VpreA		7.31 (4.58–10.04)	8.94 (6.17–11.71)	10.33 (7.60–13.06)	9.33 (6.59–12.06)	10.89 (8.16–13.62)^a)	11.79 (9.07–14.53)^a)	11.75 (9.02–14.48)^a)
Vmax		11.05 (7.03–15.08)	16.63 (12.54–20.71)^a)	19.19 (15.17–23.22)^a)	16.59 (12.57–20.62)^a)	18.83 (14.81–22.86)^a)	21.19 (17.17–25.22)^a)	20.51 (16.48–24.53)^a)
Fractional volume change (%)
	Total	43.6 (38.7–48.4)	58.1 (52.9–63.2)^a)	58.8 (53.9–63.6)^a)	59.9 (55–64.8)^a)	60.1 (55.3–65)^a)	59.2 (54.4–64.1)^a)	57.4 (52.5–62.3)^a)
	Passive	32.3 (26.1–38.5)	45.8 (39.4–52.2)^a)	46.7 (40.5–52.8)^a)	43.9 (37.7–50.1)^a)	42.7 (36.5–48.9)^a)	44.9 (38.7–51.1)^a)	43.3 (37.1–49.5)^a)
	Active	16.5 (10.2–22.7)	22.9 (16.4–29.4)	22.6 (16.4–28.9)	28.3 (22.1–34.6)^a)	29.7 (23.5–35.9)^a)	25.5 (19.3–31.8)^a)	24.2 (17.9–30.5)^a)

a) Value differs significantly (P<0.05) from corresponding baseline value. LA-FVC_total, LA-FVC_passive, LA-FVC_active represent left atrial fractional volume change during reservoir, conduit and booster pump function, respectively.