Table 2. Apparent kinetic parameters for metabolism of ethoxyresorufin in polymorphic variants of CYP1A2.

	Km	Vmax	Vmax/Km
*1	0.99 ± 0.09a)	66.9 ± 2.2ac)	67.7 ± 2.2a)
*2	1.29 ± 0.13a)	58.2 ± 2.2c)	45.3 ± 1.6b)
*3	1.25 ± 0.15a)	85.0 ± 4.0a)	68.8 ± 3.8ac)
*4	1.42 ± 0.11b)	82.2 ± 2.5a)	63.9 ± 1.8ab)
*5	1.22 ± 0.12a)	96.4 ± 3.6b)	78.2 ± 3.5c)

Different letters on the shoulder of each figure indicate significant difference to other letters (P<0.05). Vmax (pmol/min/pmol P450). Km (µM). Values are average of four different preparation of recombinant alleles of CYP1A2 (N=4, mean ± SEM).