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. 2019 Jul 24;9:10735. doi: 10.1038/s41598-019-47121-8

Table 4.

Functional mutation comparison between total genes and R genes.

#Genes #Functional
mutations		 Functional
mutations/Genes		 P values
(χ2 test)
Total gene 34,584 79,296 2.29 <2.20 × 10−16
NBS R gene 535 9,006 16.83
R singleton 232 2,734 11.78 3.68 × 10−10
R TD 303 6,272 20.70