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. 2019 Jul 24;9:10744. doi: 10.1038/s41598-019-47211-7

Table 1.

Studies reporting survival data and prognostic factors for GSM patients.

Study Year of publication No. of patients Survival data Prognostic factors
Kozak et al.2 2009 353

9 months

(median OS)

Younger age, RT,

Extent of resection

Singh et al.11 2012 22 18.5 months (median OS) TMZ
Walker et al.10 2013 46 12.5 months(median OS) TMZ
Rath et al.24 2015 27 16.7 months (median OS) TMZ
Castelli et al.17 2016 75 13 months (median OS) RT, Treatment at recurrence
Adeberg et al.9 2016 37 13.4 months (median OS) Trimodality therapy
Ma et al.8 2017 33 6.6 months (median OS)

Age <50 years,

Trimodality therapy

Frandsen et al.18 2018 1102 10.7 months (median OS)

Age <65 years,

Female sex,

Fewer comorbidities,

Trimodality therapy,

GTR

Our series 498 12.0 months (median DSS)

Age at presentation,

Tumour size,

Metastasis state,

Chemotherapy