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. 2019 Jun 24;5(2):129–138. doi: 10.1016/j.cdtm.2019.05.003

Table 3.

Number (%) of patients reporting a symptom on at least a weekly basis and factor loadings.a

Item no. Symptom Frequency (%) of symptom reported at least weekly
Factor loading on the first unrotated factor
All (n = 1751) Any-IBS (n = 1122) Any-FMS (n = 1127) Any-CFS (n = 619) Any-IBS (n = 1122) Any-FMS (n = 1127) Any-CFS (n = 619)
13 Waking up still feeling tired 1629 (93.0) 1019 (90.8) 1111 (98.5) 603 (97.4) 0.65 0.41 0.38
10 Fatigue for no reason 1566 (89.5) 961 (85.7) 1095 (97.1) 602 (97.3) 0.73 0.51 0.37
15 Difficulty concentrating 1489 (85.1) 910 (81.1) 1066 (94.6) 587 (94.9) 0.77 0.59 0.57
14 Mental fog 1481 (84.6) 902 (80.5) 1061 (94.1) 583 (94.2) 0.75 0.57 0.54
11 Fatigue increasing the day after you are active 1471 (84.1) 872 (77.8) 1078 (95.7) 602 (97.3) 0.74 0.48 0.38
16 Memory problems 1455 (83.1) 883 (78.7) 1050 (93.4) 574 (92.7) 0.73 0.52 0.52
38 Waking up often at night 1449 (82.7) 906 (80.7) 1032 (91.6) 521 (84.2) 0.54 0.38 0.44
17 Easily feel too cold 1407 (80.4) 883 (78.7) 984 (87.4) 526 (85.0) 0.52 0.33 0.42
9 Pain increasing the day after you are active 1398 (79.8) 818 (72.9) 1070 (94.9) 558 (90.2) 0.77 0.48 0.57
23 Bloating of the stomach 1366 (78.0) 970 (86.5) 893 (79.2) 466 (75.3) 0.36 0.50 0.50
2 Pain in legs and arms which is not due to hard exercise 1357 (77.5) 648 (71.1) 1070 (94.9) 520 (84.0) 0.77 0.48 0.62
7 Back pain 1348 (77.0) 842 (75.1) 1020 (90.6) 486 (78.6) 0.66 0.44 0.56
19 Easily feel too hot/sweating 1340 (76.5) 841 (74.9) 958 (85.0) 510 (82.4) 0.60 0.42 0.47
18 Very cold hands or feet 1339 (76.5) 847 (75.5) 933 (82.8) 499 (80.6) 0.49 0.37 0.45
37 Difficulty getting to sleep 1325 (75.7) 830 (73.9) 957 (84.9) 504 (81.4) 0.62 0.43 0.51
3 Pain moving from one place of body to another on different days 1268 (72.4) 752 (67) 1022 (90.7) 486 (78.6) 0.76 0.46 0.64
36 Sensitivity to noise 1264 (72.2) 769 (68.5) 937 (83.0) 519 (83.8) 0.72 0.58 0.60
5 Stomach pain 1233 (70.4) 910 (81.1) 799 (70.9) 421 (68.0) 0.38 0.60 0.57
8 Sensitive or tender skin 1229 (70.2) 750 (66.8) 969 (86.0) 447 (72.2) 0.70 0.49 0.64
29 Irritable 1220 (69.6) 786 (70.0) 860 (76.2) 434 (70.1) 0.57 0.54 0.53
35 Sensitivity to bright lights 1178 (67.2) 718 (64.0) 888 (78.8) 487 (83.8) 0.73 0.59 0.60
30 Jittery, easily startled, often worried 1175 (67.1) 765 (68.2) 840 (74.5) 423 (68.4) 0.61 0.58 0.58
34 More clumsy than others 1161 (66.3) 713 (63.5) 869 (77.0) 482 (77.8) 0.70 0.58 0.57
20 Thirsty all the time 1154 (65.9) 736 (65.5) 865 (76.7) 440 (71.1) 0.61 0.45 0.51
56 Numbness, tingling, pins and needles 1153 (65.9) 703 (62.7) 894 (79.3) 446 (72.1) 0.76 0.58 0.68
4 Headaches 1149 (65.6) 722 (64.3) 588 (74.5) 453 (73.2) 0.59 0.50 0.52
28 Feeling anxious for no reason 1125 (64.3) 743 (66.2) 793 (70.4) 395 (63.8) 0.54 0.53 0.52
44 Itchy skin 1122 (64.1) 735 (65.5) 836 (74.2) 421 (68.0) 0.61 0.53 0.60
26 Intolerant to some food 1082 (61.8) 806 (71.8) 655 (58.1) 406 (65.6) 0.21 0.36 0.34
45 Itchy eyes 1013 (57.8) 664 (59.2) 756 (67.1) 388 (62.7) 0.58 0.53 0.61
22 Constipation 1002 (57.2) 709 (63.2) 710 (63.0) 347 (56.1) 0.37 0.37 0.41
59 Feeling out of breath for no reason 989 (56.4) 628 (56.0) 739 (65.6) 432 (69.8) 0.70 0.63 0.56
39 Racing heart 959 (54.8) 608 (54.2) 688 (61.0) 391 (63.2) 0.61 0.57 0.49
1 Swollen painful joints 953 (54.5) 582 (51.9) 766 (68.0) 355 (57.4) 0.59 0.38 0.54
55 Cramps in leg, foot or bottom 947 (54.1) 601 (53.5) 743 (65.9) 357 (57.6) 0.68 0.59 0.66
32 Very vivid dreams 944 (53.9) 608 (54.3) 656 (58.2) 381 (61.5) 0.47 0.46 0.45
61 Feeling very ill for no reason 937 (53.4) 579 (51.6) 689 (61.2) 446 (51.0) 0.73 0.62 0.52
27 Depression 920 (52.6) 603 (53.8) 690 (61.2) 330 (53.4) 0.55 0.48 0.50
25 Nausea for no reason 917 (52.4) 619 (55.1) 625 (55.5) 376 (60.7) 0.57 0.60 0.56
12 Fatigue increasing after a cold or sore throat 910 (52.0) 558 (49.8) 691 (61.3) 396 (64.0) 0.61 0.42 0.37
21 Diarrhoea 874 (49.9) 684 (61.0) 518 (45.9) 281 (45.4) 0.09 0.38 0.34
42 Blocked nose 871 (49.7) 575 (51.3) 651 (57.8) 336 (54.3) 0.48 0.42 0.43
58 Urinating two or more times per night 854 (48.8) 563 (50.1) 639 (56.7) 330 (53.3) 0.46 0.41 0.46
41 Face flushes 848 (48.4) 536 (47.7) 638 (56.7) 314 (50.8) 0.54 0.44 0.51
40 Hands tremble or shake 838 (47.8) 529 (47.2) 655 (58.1) 349 (56.4) 0.69 0.63 0.59
31 Ringing in ears 823 (47.1) 518 (46.2) 603 (53.5) 347 (56.1) 0.45 0.37 0.41
24 Heartburn 819 (46.8) 569 (50.7) 579 (79.2) 272 (43.9) 0.39 0.39 0.44
43 Running nose 786 (44.9) 533 (47.5) 572 (50.8) 296 (47.8) 0.42 0.40 0.40

6 Chest pain 733 (41.8) 475 (42.3) 577 (51.2) 293 (47.4) 0.64 0.57 0.55
54 Feeling faint 658 (37.6) 419 (37.4) 461 (40.9) 333 (53.8) 0.62 0.60 0.52
52 Twitching other than eyelid 558 (31.9) 349 (31.1) 459 (40.7) 265 (42.8) 0.64 0.54 0.56
51 Twitching of eyelid 546 (31.3) 348 (31.0) 434 (38.4) 238 (38.4) 0.61 0.55 0.55
33 Nightmares/night terrors 480 (27.4) 316 (28.2) 353 (31.2) 206 (33.2) 0.53 0.52 0.55
60 Double vision 469 (26.8) 297 (26.6) 372 (33.0) 233 (37.7) 0.59 0.52 0.55
50 Boils or pimples on face or body 448 (25.6) 294 (26.3) 309 (27.4) 196 (31.7) 0.37 0.35 0.34
53 Choking sensations 409 (23.4) 291 (25.9) 413 (29.7) 169 (27.3) 0.58 0.53 0.57
49 Skin rash 365 (20.8) 252 (22.5) 266 (23.6) 146 (23.6) 0.44 0.41 0.41
46 Head colds, sore throat, flu 353 (20.2) 234 (20.9) 260 (23.0) 191 (30.9) 0.52 0.50 0.49
47 Mouth ulcers, sores in mouth 268 (15.3) 177 (15.8) 214 (19.0) 108 (17.5) 0.43 0.41 0.42
57 Loss of voice 259 (14.8) 177 (15.8) 214 (19.0) 113 (18.3) 0.49 0.41 0.40
48 Cold sores on or near lips 79 (4.5) 54 (4.8) 65 (5.8) 34 (5.4) 0.34 0.30 0.33

IBS: irritable bowel syndrome; FMS: fibromyalgia syndrome; CFS: chronic fatigue syndrome.

a

The groups refer to participants reporting a diagnosis of IBS, FMS and CFS, irrespective of whether the participant reports other additional functional disorders.