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. 2019 Jul 18;10:823. doi: 10.3389/fphys.2019.00823

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Copyright © 2019 Li and Finley.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The outcomes of anti-angiogenic factor secretion in different microenvironments. Column I shows the condition of low HSPG level and Column II shows the condition of high HSPG level. (A) Before the secretion of anti-angiogenic factors. (B) After the secretion of anti-angiogenic factors.