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. 2019 May 22;8(7):500–510. doi: 10.1002/psp4.12414

Figure 1.

Figure 1

Observed plasma and CSF dose‐normalized concentration after last fluconazole dose for preterm and term infants. Dose‐normalized concentration vs. time from last dose observed from preterm and term infants enrolled in the prophylaxis and PPRU studies following various treatment and prophylactic fluconazole dosing regimens for plasma (a) and CSF (b) samples. CSF, cerebrospinal fluid; hr, hour; PPRU, Pediatric Pharmacology Research Unit.