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. 2019 Jul 25;16:154. doi: 10.1186/s12974-019-1521-5

Table 2.

Baseline OCT results of MOG-IgG-seropositive patients and HCs

Baseline results HC MOG-IgG-seropositive patients EyeON- MOG-IgG-seropositive patients
EyeON+
HC vs EyeON- HC vs EyeON+ EyeON- vs EyeON+
N (eyes) = 56 N (eyes) = 18 N (eyes) = 20 [B] [SE] [p] [B] [SE] [p] [B] [SE] [p]
GCIP [mean (SD)] 0.63 (0.04) 0.57 (0.07) 0.39 (0.12) − 0.057 0.022 0.008 − 0.235 0.033 < 0.0001 − 0.178 0.037 < 0.0001
pRNFL [mean (SD)] 98.50 (9.17) 94.33 (15.92) 58.25 (22.56) − 4.167 4.577 0.360 − 40.25 5.864 < 0.0001 − 36.08 6.311 < 0.0001
INL [mean (SD)] 0.27 (0.03) 0.26 (0.03) 0.30 (0.05) − 0.014 0.009 0.110 0.026 0.013 0.046 0.041 0.014 0.004
MV [mean (SD)] 2.37 (0.10) 2.34 (0.11) 2.19 (0.13) − 0.036 0.034 0.290 − 0.183 0.039 < 0.0001 − 0.147 0.042 0.0005
HCVA in logMAR [mean (SD)] −0.09 (0.14) 0.05 (0.15) 0.55 (0.81) 0.146 0.059 0.013 0.394 0.134 0.0032 0.248 0.131 0.058

Abbreviations: B estimate, GCIP combined ganglion cell and inner plexiform layer, HC healthy control, INL inner nuclear layer, EyeON- MOG-IgG-seropositive patients without a history of ON, EyeON+ MOG-IgG-seropositive patients with a history of ON, OCT optical coherence tomography, ON optic neuritis, p p value, pRNFL peripapillary retinal nerve fiber layer, SD standard deviation, SE standard error, MV macular volume, vs versus, N number of eyes