Table 2.
Baseline OCT results of MOG-IgG-seropositive patients and HCs
Baseline results | HC | MOG-IgG-seropositive patients EyeON- | MOG-IgG-seropositive patients EyeON+ |
HC vs EyeON- | HC vs EyeON+ | EyeON- vs EyeON+ | ||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
N (eyes) = 56 | N (eyes) = 18 | N (eyes) = 20 | [B] | [SE] | [p] | [B] | [SE] | [p] | [B] | [SE] | [p] | |
GCIP [mean (SD)] | 0.63 (0.04) | 0.57 (0.07) | 0.39 (0.12) | − 0.057 | 0.022 | 0.008 | − 0.235 | 0.033 | < 0.0001 | − 0.178 | 0.037 | < 0.0001 |
pRNFL [mean (SD)] | 98.50 (9.17) | 94.33 (15.92) | 58.25 (22.56) | − 4.167 | 4.577 | 0.360 | − 40.25 | 5.864 | < 0.0001 | − 36.08 | 6.311 | < 0.0001 |
INL [mean (SD)] | 0.27 (0.03) | 0.26 (0.03) | 0.30 (0.05) | − 0.014 | 0.009 | 0.110 | 0.026 | 0.013 | 0.046 | 0.041 | 0.014 | 0.004 |
MV [mean (SD)] | 2.37 (0.10) | 2.34 (0.11) | 2.19 (0.13) | − 0.036 | 0.034 | 0.290 | − 0.183 | 0.039 | < 0.0001 | − 0.147 | 0.042 | 0.0005 |
HCVA in logMAR [mean (SD)] | −0.09 (0.14) | 0.05 (0.15) | 0.55 (0.81) | 0.146 | 0.059 | 0.013 | 0.394 | 0.134 | 0.0032 | 0.248 | 0.131 | 0.058 |
Abbreviations: B estimate, GCIP combined ganglion cell and inner plexiform layer, HC healthy control, INL inner nuclear layer, EyeON- MOG-IgG-seropositive patients without a history of ON, EyeON+ MOG-IgG-seropositive patients with a history of ON, OCT optical coherence tomography, ON optic neuritis, p p value, pRNFL peripapillary retinal nerve fiber layer, SD standard deviation, SE standard error, MV macular volume, vs versus, N number of eyes