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. 2019 Jul 25;16:154. doi: 10.1186/s12974-019-1521-5

Table 3.

Longitudinal OCT results of MOG-IgG-seropositive patients and HCs

Longitudinal OCT data HC MOG-IgG-seropositive patients EyeON- MOG-IgG-seropositive patients EyeON+ HC vs MOG-IgG-seropositive patients (EyeON- and EyeON+) EyeON- vs EyeON+
Absolute change to baseline
N (eyes) = 56 N (eyes) = 18 N (eyes) = 20 [B] [95%CI] [SE] [p] [B] [95%CI] [SE] [p]
GCIP [mean (SD)] 0.00 (0.01) 0.00 (0.01) 0.00 (0.05) − 0.000 − 0.004; 0.005 0.002 0.884 − 0.006 − 0.016; 0.003 0.005 0.214
pRNFL [mean (SD)] − 0.61 (2.00) − 4.5 (5.89) − 1.60 (4.48) − 1.645

− 2.819;

− 0.471

0.599 0.009 0.168 − 1.380; 1.717 0.790 0.832
INL [mean (SD)] 0.00 (0.01) 0.01 (0.02) 0.00 (0.03) 0.002 −0.002; 0.005 0.002 0.312 − 0.003

− 0.011;

0.004

0.004 0.381
MV [mean (SD)] 0.00 (0.02) − 0.01 (0.04) − 0.01 (0.05) − 0.008 − 0.016; 0.0013 0.004 0.103 0.002 − 0.013; 0.018 0.008 0.769

Abbreviations: 95%CI 95% confidence interval, B Estimate (beta-coefficient), GCIP combined ganglion cell and inner plexiform layer, HC healthy control, INL inner nuclear layer, EyeON- MOG-IgG-seropositive patients without a history of ON, EyeON+ MOG-IgG-seropositive patients with a history of ON, OCT optical coherence tomography, p p value, pRNFL peripapillary retinal nerve fiber layer, SD standard deviation, SE standard error, MV macular volume, vs versus, N number of eyes