Table 2.
Clinicopathologic data | Total (n = 130) |
Median age (range) | 67 (37-88) |
Male | 79 (60.8) |
Primary site | |
Rectum | 60 (46.2) |
Positive lymph nodes | 76 (58.5) |
Stage according to AJCC | |
I | 1 (0.8) |
II | 54 (41.5) |
III | 75 (57.7) |
Histological grade | |
I + II | 83 (63.8) |
III + IV | 47 (36.2) |
KRAS mutation | 48 (36.9) |
BRAF V600E mutation | 5 (3.8) |
TYMS LOH | 34 (26.2) |
Overall survival | |
Deaths n (%) | 45 (34.6) |
Mean time month (95%CI) | 110.0 (99.5-120.5) |
Disease-free survival | |
Events n (%) | 51 (39.2) |
Mean time month (95%CI) | 100.1 (88.3-112.0) |
Median follow up in months (range) | 71.2 (0.5-156.8) |
AJCC: American Joint Committee on Cancer 7th edition; TYMS: Thymidylate synthase gene; LOH: Loss of heterozygosity; CI: Confidence interval.