Table 1.

Content of arsenic species in the livers of rats from 0 h to 48 h after a single administration of realgar (n = 6, 3 males and 3 females per group, $\overline{x}$ ± SD).

Time	AsC	AsB	As(III)	DMA	MMA	As(V)	tAs
0 h	0.00 ± 0.00	0.03 ± 0.01	0.00 ± 0.00	0.28 ± 0.04	0.02 ± 0.02	0.03 ± 0.05	0.82 ± 0.29
0.25 h	0.00 ± 0.00	0.04 ± 0.01	2.54 ± 1.33*	0.67 ± 0.38	0.34 ± 0.14	0.12 ± 0.04**	5.16 ± 1.91**
0.5 h	0.00 ± 0.00	0.02 ± 0.01	4.03 ± 1.91**	0.63 ± 0.26*	0.49 ± 0.12*	0.27 ± 0.11***	7.55 ± 1.82**
1 h	0.00 ± 0.00	0.02 ± 0.01	2.58 ± 0.98**	0.91 ± 0.99	0.49 ± 0.14**	0.16 ± 0.04***	6.72 ± 2.34**
2 h	0.00 ± 0.00	0.02 ± 0.01	2.62 ± 1.48**	1.51 ± 0.36**	0.44 ± 0.23*	0.12 ± 0.08*	6.98 ± 2.79**
4 h	0.00 ± 0.00	0.03 ± 0.01	0.89 ± 0.31**	1.52 ± 0.17**	0.17 ± 0.06	0.10 ± 0.05*	5.18 ± 0.71**
8 h	0.00 ± 0.00	0.02 ± 0.01	0.30 ± 0.04**	1.86 ± 0.17*	0.06 ± 0.06	0.05 ± 0.05	4.14 ± 0.73**
16 h	0.00 ± 0.00	0.02 ± 0.01	0.20 ± 0.04*	2.58 ± 0.17**	0.03 ± 0.03	0.03 ± 0.04	4.30 ± 0.82**
32 h	0.00 ± 0.00	0.04 ± 0.02	0.07 ± 0.04*	1.74 ± 0.28**	0.01 ± 0.02	0.03 ± 0.03	2.93 ± 0.73*
48 h	0.00 ± 0.00	0.03 ± 0.01	0.06 ± 0.04*	1.39 ± 0.89**	0.02 ± 0.01	0.04 ± 0.06	2.09 ± 1.17*

All values are expressed as the means (M) ± standard deviation (SD). ^*p <0.05, ^**p < 0.01, ^***p < 0.001. Values are compared with the content at 0 h. Differences were analysed by a one-way analysis of variance.