Table 12.
Relative organ weights data from the oral administration of realgar for 30 days in male rats (%).
Item | Control | Realgar |
||
---|---|---|---|---|
10.6 mg/kg | 40.5 mg/kg | 170 mg/kg | ||
Heart | 0.323 ± 0.033 | 0.334 ± 0.020 | 0.311 ± 0.022 | 0.317 ± 0.020 |
Liver | 2.952 ± 0.247 | 3.012 ± 0.120 | 3.082 ± 0.198 | 2.514 ± 0.860 |
Spleen | 0.250 ± 0.030 | 0.230 ± 0.167 | 0.235 ± 0.016 | 0.269 ± 0.037 |
Lung | 0.415 ± 0.046 | 0.429 ± 0.043 | 0.433 ± 0.033 | 0.435 ± 0.028 |
Kidney | 0.746 ± 0.034 | 0.686 ± 0.164 | 0.728 ± 0.035 | 0.730 ± 0.061 |
Brain | 0.522 ± 0.034 | 0.560 ± 0.044 | 0.544 ± 0.026 | 0.551 ± 0.058 |
Stomach | 0.018 ± 0.003 | 0.020 ± 0.003 | 0.020 ± 0.003 | 0.018 ± 0.004 |
Adrenal gland | 0.376 ± 0.120 | 0.401 ± 0.092 | 0.352 ± 0.085 | 0.389 ± 0.099 |
Thymus | 0.944 ± 0.067 | 0.778 ± 0.435 | 0.902 ± 0.144 | 1.035 ± 0.058 |
Testis | 0.256 ± 0.086 | 0.211 ± 0.035 | 0.194 ± 0.017* | 0.230 ± 0.048 |
Epididymis | 0.205 ± 0.056 | 0.182 ± 0.020 | 0.170 ± 0.074 | 0.162 ± 0.060 |
All values are expressed as the means (M) ± standard deviation (SD). *p < 0.05, **p < 0.01, ***p < 0.001. Values are compared with those of the control group. Differences were analysed by a one-way analysis of variance.