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. 2019 Jul 20;12(10):1305–1313. doi: 10.1016/j.tranon.2019.05.016

Fig. 3.

Fig. 3

Circ-UBE2D2 functions as a sponge of miR-1236 and miR-1287. (A, B) qRT-PCR analysis of the expression of miR-370, miR-1236, and miR-1287 in circ-UBE2D2-knockdown (A)/overexpressing (B) BT-474 and MDA-MB-231 cells. (C, D) The luciferase activity of BT-474 and MDA-MB-231 cells cotransfected with wild-type or mutant circ-UBE2D2 luciferase vector and control or miR-1236 (C)/miR-1287 (D) mimics. (E, F) qRT-PCR analysis of the expression of reported miR-1236 (E)/miR-1287 (F) target genes in circ-UBE2D2–overexpressing BT-474 and MDA-MB-231 cells transfected with or without miR-1236/miR-1287. NC = negative control. *P < .05, **P < .01.