Table II.
Echocardiographic parameters in patients with Wilson’s disease and control subjects
| Parameter | Wilson’s disease (n = 125) | Control group (n = 125) | P-value |
|---|---|---|---|
| LVDD [cm] | 4.85 ±0.54 | 4.84 ±0.34 | NS |
| LVSD [cm] | 2.95 ±0.4 | 2.9 ±0.25 | NS |
| IVSD [cm] | 0.99 ±0.14 | 0.96 ±0.12 | NS |
| PWD [cm] | 1.0 ±0.13 | 0.93 ±0.12 | 0.00003 |
| LA [cm] | 3.55 ±0.49 | 3.56 ±0.3 | NS |
| LVM [g] | 174.89 ±48.31 | 162.8 ±39.14 | 0.037 |
| LVMI [g/m2] | 96.58 ±22.64 | 90.72 ±19.76 | 0.05 |
| EF [%] | 67.5 ±6.5 | 67.7 ±5.3 | NS |
| E [m/s] | 0.76 ±0.13 | 0.76 ±0.12 | NS |
| A [m/s] | 0.51 ±0.09 | 0.54 ±0.1 | 0.04 |
| E/A ratio | 1.53 ±0.36 | 1.47 ±0.31 | NS |
| DecT [ms] | 199.5 ±32.25 | 194.15 ±26.33 | NS |
| Septal S [m/s] | 0.08 ±0.07 | 0.1 ±0.01 | NS |
| Septal e’ [m/s] | 0.11 ±0.02 | 0.12 ±0.03 | NS |
| Septal a’ [m/s] | 0.08 ±0.01 | 0.08 ±0.01 | NS |
| e’/a’ ratio | 1.5 ±0.38 | 1.5 ±0.48 | NS |
| E/septal e’ ratio | 6.9 ±1.52 | 6.83 ±1.54 | NS |
| Lateral S [m/s] | 0.11 ±0.02 | 0.11 ±0.02 | NS |
| Lateral e’ [m/s] | 0.16 ±0.03 | 0.17 ±0.03 | 0.01 |
| Lateral a’ [m/s] | 0.08 ±0.02 | 0.08 ±0.01 | NS |
| Lateral e’/a’ ratio | 1.96 ±0.58 | 2.1 ±0.51 | 0.036 |
Data are presented as mean ± standard deviation. A p-value of < 0.05 is considered statistically significant. LVDD – left ventricular diastolic diameter, LVSD – left ventricular systolic diameter, IVSD – interventricular septum in diastole, PWD – posterior wall in diastole, LA – left atrial dimension, LVM – left ventricular mass, LVMI – left ventricular mass index, EF – ejection fraction of the left ventricle, E – peak early velocity of mitral inflow, A – peak late velocity of mitral inflow, DecT – E wave deceleration time, S – peak systolic velocity of the mitral annulus, e’ – early diastolic velocity of the mitral annulus, a’ – late diastolic velocity of the mitral annulus.