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Mediation on effects of SOD1 on MMSE and Precuneus GM by tau. Preacher–Hayes mediation of CSF SOD1, total tau, and MMSE scores at baseline (A). Preacher–Hayes mediation of CSF SOD1, CSF total tau, and regional GM volume in left precuneus in a submaximum voxel (−10.5, −49.5, 72) (B). **p < 0.01, ***p < 0.001. MMSE, Mini-Mental State Examination. Color images are available online.
