Table 1.
Demographic Data for Alzheimer's Disease Neuroimaging Initiative Subjects with Cerebrospinal Fluid Superoxide Dismutase 1
| CU (n = 86) | MCI (n = 135) | AD (n = 66) | |
|---|---|---|---|
| Age (years) | 75.70 ± 5.54 | 74.67 ± 7.32 | 75.04 ± 7.62 |
| Education (years) | 15.64 ± 2.97 | 16.02 ± 2.97 | 15.06 ± 2.93 |
| Sex (% female)* | 48.8% | 32.6% | 43.9% |
| BMI (kg/m2) | 26.54 ± 3.84 | 25.98 ± 3.77 | 26.36 ± 4.28 |
| APOE4 carriage (%)*** | 24.4% | 52.6% | 71.2% |
| CSF SOD (AU) | 21.46 ± 0.34 | 21.49 ± 0.37 | 21.42 ± 0.39 |
| CDR-sob (score)*** | 0.02 ± 0.11 | 1.54 ± 0.86 | 4.37 ± 1.54 |
| ADAS-cog11 (score)*** | 6.05 ± 2.90 | 11.73 ± 4.33 | 18.86 ± 6.73 |
| EF factor (z-score)*** | 0.66 ± 0.62 | −0.08 ± 0.73 | −1.02 ± 0.81 |
| Memory factor (z-score)*** | 0.98 ± 0.50 | −0.15 ± 0.57 | −0.90 ± 0.56 |
| MMSE (score)*** | 29.05 ± 1.02 | 26.92 ± 1.74 | 23.50 ± 1.83 |
Values are mean ± standard deviation unless otherwise stated.
*,***
Chi-square p < 0.05, <0.001.
AD, Alzheimer's disease; ADAS-cog, Alzheimer's Disease Assessment Scale-cognitive subscale; APOE, apolipoprotein E; AU, arbitrary units; BMI, body mass index; CDR-sob, Clinical Dementia Rating Scale Sum of Boxes; CSF, cerebrospinal fluid; CU, cognitively unimpaired; EF, executive function; MCI, mild cognitive impairment; MMSE, Mini-Mental State Examination; SOD, superoxide dismutase.