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. 2019 Aug;10(4):751–765. doi: 10.21037/jgo.2019.03.10

Table S1. Terms employed for database searches.

Search number Search terms Hits
Embase
   1 exp bile duct carcinoma/ 19,619
   2 (cholangiocarcinoma or hepatocholangiocarcinoma).mp 14,543
   3 exp bile duct/ 23,896
   4 ((bile duct or cholangiocellular or klatskin or biliary or hepatobiliary or cholangiolar) and (cancer* or carcinoma* or neoplasm* or tumor* or tumour*)).mp. 53,832
   5 or/1−4 70,319
   6 exp isocitrate dehydrogenase 1/ 2,649
   7 (isocitrate dehydrogenase 1 or IDH1 or IDH-1).mp. 5,973
   8 6 or 7 5,973
   9 5 and 8 176
   10 limit 9 to English language 175
MEDLINE via Ovid
   1 exp Adenoma, Bile Duct/ or exp Cholangiocarcinoma/ or exp Bile Duct Neoplasms/ 20,176
   2 (Cholangiocarcinoma or hepatocholangiocarcinoma).mp. [mp=title, abstract, original title, name of substance word, subject heading word, keyword heading word, protocol supplementary concept word, rare disease supplementary concept word, unique identifier, synonyms] 12,364
   3 exp Bile Ducts/ 48,387
   4 ((bile duct or cholangiocellular or klatskin or biliary or hepatobiliary or cholangiolar) and (cancer* or carcinoma* or neoplasm* or tumor* or tumour*)).mp. 41,358
   5 or/1−4 77,568
   6 (isocitrate dehydrogenase 1 or IDH1 or IDH-1).mp. 2,601
   7 5 and 6 81
   8 limit 7 to English language 81
Cochrane Library
   1 MeSH descriptor: [Adenoma, Bile Duct] explode all trees 6
   2 MeSH descriptor: [Cholangiocarcinoma] explode all trees 82
   3 MeSH descriptor: [Bile Ducts] explode all trees 493
   4 Cholangiocarcinoma or hepatocholangiocarcinoma 333
   5 ((bile duct or cholangiocellular or klatskin or biliary or hepatobiliary or cholangiolar) and (cancer* or carcinoma* or neoplasm* or tumor* or tumour*)) 2,160
   6 #1 or #2 or #3 or #4 or #5 2,541
   7 MeSH descriptor: [Isocitrate Dehydrogenase] explode all trees 24
   8 (isocitrate dehydrogenase 1 or IDH1 or IDH-1) 145
   9 #7 or #8 153
   10 #6 and #9 11
PubMed
   1 ((bile duct carcinoma[MeSH Terms]) OR bile duct adenoma[MeSH Terms]) OR cholangiocarcinoma[MeSH Terms] 18,209
   2 bile duct[MeSH Terms] 44,347
   3 (bile duct or cholangiocellular or klatskin or biliary or hepatobiliary or cholangiolar 158,094
   4 ((((cancer*) OR carcinoma*) OR neoplasm*) OR tumor*) OR tumour* 3,668,071
   5 #3 and #4 51,211
   6 Cholangiocarcinoma or hepatocholangiocarcinoma 11,521
   7 #1 or #2 or #5 or #6 83,317
   8 (((isocitrate dehydrogenase i[MeSH Terms]) OR isocitrate dehydrogenase 1) OR IDH1) OR IDH-1 7,408
   9 #7 and #8 91
   10 #9 Filters: English 90
   11 #10 Filters: Publication date from 2016/01/01 to 2017/12/31 41