Table 3. Fusion genes detected by RNA sequencing.
Gene | Fusions | Total tested | Frequency, % | IHCC fusions | EHCC fusions | GBC fusions |
---|---|---|---|---|---|---|
BRAF | 2 | 131 | 1.5 | SND1-BRAF | – | CUX1-BRAF |
FGFR2 | 7 | 149 | 4.7 | FGFR2-AHCYL1 FGFR2-AXDND1 FGFR2-FMR1 FGFR2-PAWR FGFR2-MYLK | FGFR2-ADAM9 | FGFR2-BICC1 |
FGFR3 | 1 | 149 | 0.7 | – | – | FGFR3-TACC3 |
IHCC, intrahepatic cholangiocarcinoma; EHCC, extrahepatic cholangiocarcinoma; GBC, gallbladder carcinoma.