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. 2019 Aug;10(4):605–615. doi: 10.21037/jgo.2019.02.17

Table 3. Toxicities.

Variable Cap (N=36), n [%] 5-FU (N=32), n [%] Total (N=68), n [%] P value
Hematological toxicities (≥ grade 3)
   Neutropenia 5 [14] 6 [19] 11 [16] 0.744
   Anemia 3 [8] 2 [6] 5 [7] 0.557
   Thrombocytopenia 0 [0] 1 [3] 1 [1] 0.471
Common non-hematological toxicities
   Radiation dermatitis 0.740
      Grade 2 13 [36] 11 [34] 24 [35]
      Grade 3 14 [39] 15 [47] 29 [43]
   Anal pain 0.159
      Grade 2 28 [78] 18 [56] 46 [68]
      Grade 3 3 [8] 4 [13] 7 [10]
   Diarrhea 0.556
      Grade 2 12 [33] 15 [47] 27 [40]
      Grade 3 6 [17] 5 [16] 11 [16]
   Nausea 0.236
      Grade 2 9 [25] 3 [9] 12 [18]
      Grade 3 2 [6] 2 [6] 4 [6]
Uncommon non-hematological toxicities (≥ grade 2)
   Stomatitis 2 [6] 10 [31] 12 [18] 0.009
   Skin/soft tissue infection 3 [8] 2 [6] 5 [7] 1.000
   Cystitis 8 [22] 4 [13] 12 [18] 0.353
   Proctitis 4 [11] 2 [6] 6 [9] 0.676
   Deep vein thrombosis 0 [0] 4 [13] 4 [6] 0.044
   Acute coronary syndrome 2 [6] 2 [6] 4 [6] 1.000
   Hand and foot syndrome 4 [11] 5 [16] 9 [13] 0.725

Cap, capecitabine; 5-FU, 5 fluorouracil.