Table 2. The effect of different treatment cycles on serum levels of IL-10 and some biochemical parameters.
Parameter | At baseline | After one cycle | After two cycles | After three cycles | P value between groups |
---|---|---|---|---|---|
ALT (U/L) | 57.50 (44.25–83.25) | 52.50 (41.25–77.50)a | 54.05±16.23a,b | 44.47±10.27a,b | <0.001 |
AST (U/L) | 76.65±23.51 | 70.35±20.63a | 61.05±18.69a,b | 46.60±12.39a,b,c | <0.001 |
Albumin (g/dL) | 2.85 (2.70–3.30) | 2.98±0.48 | 3.06±0.44 | 3.10 (2.90–3.60)a,b | 0.003 |
Total bilirubin (mg/dL) | 1.84±0.77 | 1.67±0.63 | 1.36±0.52a,b | 1.02±0.27a,b,c | <0.001 |
AFU (U/L) | 610 (502.5–755.25) | 461.10±150.89a | 280 (207.0–395.0)a | 205 (125.0–287.0)a,b,c | <0.001 |
IL-10 (pg/mL) | 35.79±9.54 | 32.74±6.12 | 26.89±5.18a,b | 22.44 (17.98–26.84)a,b,c | <0.001 |
Data are expressed as mean ± SD for Gaussian variables and median (inter-quartile range) for non-Gaussian variables. In multiple comparisons: a, P<0.05 vs. baseline; b, P<0.05 vs. first cycle; c, P<0.05 vs. second cycle. ALT, alanine aminotransferase; AST, aspartate aminotransferase; AFU, alpha-L-fucosidase; IL-10, interleukin-10.