Table 3. Univariate and multivariate Cox’s regression analyses of overall survival.
| Variable | Univariate analysis | Multivariate analysis | |||
|---|---|---|---|---|---|
| HR ratio (95% CI) | P value | HR ratio (95% CI) | P value | ||
| Gender (female vs. male) | 0.85 (0.18–4.02) | 0.839 | – | – | |
| Age (>60 vs. ≤60 years) | 1.40 (0.40–4.86) | 0.594 | – | – | |
| Tumor size (>5 vs. ≤5 cm) | 1.00 (0.17–6.03) | 0.994 | – | – | |
| BCLC stage (C vs. B vs. A) | 2.51 (0.61–10.23) | 0.200 | – | – | |
| IL-10 (high vs. low) | 3.90 (0.99–15.31) | 0.051 | 10.22 (1.74–59.91) | 0.010 | |
| miR-141 (high vs. low) | 0.22 (0.05–1.06) | 0.060 | 0.71 (0.13–3.89) | 0.692 | |
| miR-21 (high vs. low) | 6.09 (1.27–29.15) | 0.024 | 12.98 (1.65–102.03) | 0.015 | |
CI, confidence interval; HR, hazard ratio; BCLC, Barcelona Clinic Liver Cancer; IL-10, interleukin-10.