Table 1.
Tuberculin skin test status among adult patients with culture-confirmed TB, Georgia, 2009 – 2014 (N=780)
| TST Results | Total N=780 N % |
P-Value (Χ2) |
||
|---|---|---|---|---|
| Patient Characteristic | Negative N % = 242 (31.0) N % |
Positive* N % = 538 (69.0) N % |
||
| Age group | ||||
| 15 – 24 | 18 (7.4) | 85 (15.8) | 103 (13.2) | <0.01 |
| 25 – 44 | 84 (34.7) | 214 (39.8) | 298 (38.2) | |
| 45 – 64 | 93 (38.4) | 184 (34.2) | 277 (35.5) | |
| ≥ 65 | 47 (19.4) | 55 (10.2) | 102 (13.1) | |
| Male Gender | 177 (73.1) | 365 (67.8) | 542 (69.5) | 0.14 |
| Race, Black | 104 (43.0) | 271 (50.5) | 375 (48.1) | 0.05 |
| Foreign-born | 84 (34.7) | 255 (47.4) | 339 (43.5) | <0.01 |
| Homeless | 37 (15.3) | 68 (12.6) | 105 (13.5) | 0.32 |
| History of imprisonment | 4 (1.7) | 39 (7.3) | 43 (5.5) | <0.01 |
| History of contact with TB patient | 19 (8.1) | 95 (18.0) | 114 (15.0) | <0.01 |
| History of TB disease | 8 (3.3) | 32 (5.9) | 40 (5.1) | 0.12 |
| Illicit drug use | 28 (11.7) | 67 (12.5) | 95 (12.2) | 0.75 |
| Alcohol abuse | 44 (18.3) | 94 (17.5) | 138 (17.8) | 0.78 |
| HIV status, Positive | 40 (17.5) | 46 (8.7) | 86 (11.4) | <0.01 |
| Diabetes | 39 (16.7) | 59 (11.2) | 98 (12.9) | 0.04 |
| ESRD | 4 (1.7) | 3 (0.6) | 7 (0.9) | 0.21¶ |
| History of LTBI prophylaxis | 2 (0.8) | 31 (5.9) | 33 (4.3) | <0.01 |
| Positive smear at baseline | 168 (69.7) | 361 (67.2) | 529 (68.0) | 0.49 |
| Abnormal CXR reading at baseline | 214 (96.0) | 475 (92.8) | 689 (93.7) | 0.10 |
| Cavitary disease | 70 (31.8) | 196 (38.5) | 266 (36.5) | 0.09 |
| Miliary disease | 15 (6.8) | 9 (1.8) | 24 (3.3) | <0.01 |
| INH-monoresistant TB | 36 (15.6) | 60 (11.6) | 96 (12.8) | 0.13 |
| TB Site | ||||
| Pulmonary | 210 (86.8) | 495 (92.0) | 705 (90.4) | 0.04 |
| Pulmonary + Extrapulmonary | 27 (11.2) | 32 (6.0) | 59 (7.6) | |
| Extrapulmonary only | 5 (2.0) | 11 (2.0) | 16 (2.1) | |
| TB Treatment Outcome | ||||
| Completed | 207 (85.5) | 505 (93.9) | 712 (91.3) | <0.01¶ |
| Died | 26 (10.7) | 18 (3.4) | 44 (5.6) | |
| Lost to follow up | 6 (2.5) | 13 (2.4) | 19 (2.4) | |
| Uncooperative/refused to continue treatment | 0 (0.0) | 1 (0.2) | 1 (0.1) | |
| Stopped due to adverse reaction | 3 (1.24) | 1 (0.2) | 4 (0.5) | |
*
Classification of positive TST results based on US Centers for Disease Control and Prevention guidelines [19]
Abbreviations: HIV – human immunodeficiency virus; ESRD – end-stage renal disease; TNF – tumor necrosis factor; LTBI – latent TB infection; TST – tuberculin skin test; CXR – chest x-ray; INH – isoniazid
Bold indicates statistical significance (two-sided P-value <0.05)