Table 1:

Recommendations for colorectal cancer screening across professional organizations

Professional organization	Recommended screening tests	Age to initiate screening	Age to stop screening	Other considerations
U.S. Preventive Services Task Force (2016) [70]	gFOBT, FIT, FIT-DNA, colonoscopy, CT colonography, sigmoidoscopy	50	75
U.S Multi-Society Task Force on Colorectal Cancer (2017) [71]	FIT, colonoscopy (Tier 1)*	50	75	Screening at age 45 years for African Americans; AGA endorses Canadian guidelines on screening in setting of family history[34]
National Comprehensive Cancer Network (2018) [72]	gFOBT, FIT, FIT-DNA, colonoscopy, CT colonography, sigmoidoscopy	50	75	Focused guidelines address screening for high-risk syndromes[35]
American College of Physicians (2012) [73]	gFOBT, FIT, FIT-DNA, colonoscopy, CT colonography, sigmoidoscopy, DCBE	50	75
Canadian Task Force on Preventive Health Care (2016) [74]	gFOBT, FIT, sigmoidoscopy	50	74	Weak recommendation for screening in ages 50-59 years
American Cancer Society (2018) [19]	gFOBT, FIT, FIT-DNA, colonoscopy, CT colonography, sigmoidoscopy	45	75	Qualified recommendation for initiating screening at age 45 years – uncertainty regarding ratio of benefits to harms

^*Tier 2 tests include CT colonography, FIT-DNA, flexible sigmoidoscopy