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The anabolism of β-Alanine biosynthesis via uracil and L-aspartate. (A) The nucleotide base uracil can be degraded to β-alanine. The enzymes in this pathway are dihydrouracil dehydrogenase [EC 1.3.1.2], dihydropyrimidinase [EC 3.5.2.2] and β-ureidopropionase [EC 3.5.1.6]. (B) Aspartate 1-decarboxylase [EC 4.1.1.11] can directly decarboxylate L-aspartate into β-alanine, which may feed into Coenzyme A biosynthesis via pantothenate.
