Table 1:
Placebo | GLC | GLP-2 | GLP-2 + GLC | SEM | P-value | |
---|---|---|---|---|---|---|
Lymph flow | ||||||
Time to peak (min) | 28.8ab | 32.7ab | 14.6b | 35.1a | 5.50 | 0.023 |
Maximal fold change | 1.39b | 2.44ab | 2.68a | 2.73ab | 0.38 | 0.033 |
Slope of rise (fold change/hr) | 1.45 | 3.93 | 6.54 | 5.01 | 1.67 | 0.125 |
Slope of decline (fold change/hr) | −1.24 | −2.21 | −1.43 | −1.31 | 0.49 | 0.334 |
Fold change at 60 minutes | 1.15b | 1.18b | 1.68ab | 2.03a | 0.20 | 0.009 |
Cumulative lymph volume at 60 minutes (ml) | 2.72b | 3.27ab | 4.40a | 4.23a | 0.39 | 0.002 |
Triglyceride concentration | ||||||
Time to peak (min) | 19.4 | 12.0 | 9.46 | 11.45 | 3.26 | 0.169 |
Maximal fold change | 0.98b | 2.21a | 1.19ab | 1.76ab | 0.29 | 0.019 |
Slope of rise (fold change/hr) | 1.45 | 5.64 | 1.91 | 4.29 | 1.86 | 0.228 |
Slope of decline (fold change/hr) | −0.94b | −2.77a | −1.32ab | −2.22ab | 0.44 | 0.018 |
Fold change at 60 minutes | 0.75 | 0.60 | 0.62 | 0.49 | 0.08 | 0.131 |
Cumulative TG mass at 60 minutes (mg) | 129 | 230 | 239 | 228 | 35.8 | 0.058 |
TG output | ||||||
Time to peak (min) | 19.9 | 22.9 | 13.9 | 18.4 | 3.87 | 0.435 |
Maximal fold change | 1.18b | 3.05a | 2.67ab | 3.17a | 0.48 | 0.021 |
Slope of rise (fold change/hr) | 1.21b | 8.07a | 6.55ab | 10.4a | 2.59 | 0.049 |
Slope of decline (fold change/hr) | −0.67b | −3.87a | −2.14ab | −3.30a | 0.64 | 0.005 |
Fold change at 60 minutes | 0.778 | 0.753 | 0.973 | 0.979 | 0.15 | 0.260 |
Superscripts of differing letters within a row indicate significant differences as identified by Tukey separation