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. 2019 May 15;170(2):404–414. doi: 10.1093/toxsci/kfz114

Figure 7.

Figure 7.

Upregulation of interleukin-33 (IL-33) expression by diesel particulate matter (DPM) in THP-1 macrophages. THP-1 macrophages were treated with DPM (5 μg/ml) or DPM extracts (DPME, 10 μg/ml) for 6 h. A and B, The mRNA expression of (A) CYP1A1 and (B) IL-33 variant 5 was evaluated by real-time PCR. The values represent the mean ± SE (n = 3). Data were analyzed using a one-way analysis of variance (ANOVA), followed by Dunnett's test. **p < .01 versus the untreated group. C and D, IL-33 protein expression was evaluated by immunoblotting. C, Representative images of immunoblotting. D, The band intensity was measured, and the protein levels of IL-33 were divided by those of α-tubulin to calculate the relative protein levels. The values represent the mean ± SE (n = 3). Data were analyzed using a one-way ANOVA, followed by Dunnett's test. **p < .01 versus the untreated group.