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. 2019 Apr 24;170(2):345–356. doi: 10.1093/toxsci/kfz102

Figure 4.

Figure 4.

Concentration-dependent effects of the 11 intermediate TdP-risk drugs on CTD90 and incidence of early afterdepolarizations (EADs) and beat stop (BS) in hSC-CMs, measured using the Ca2+ transient assay at the 3 sites. fCmax, free therapeutic plasma level in humans.