Figure 5.

The inhibitory roles of SBP in vascular inflammation. (a) The expression of inflammatory proteins was quantified by western blot. (b) The mRNA expression of VCAM-1, ICAM-1, IL-6, and IL-2 was measured by qRT-PCR. (c) The content of macrophages in the lesion area of aortic sinus was investigated by immunohistochemical analysis for CD68 which was a hallmark of macrophages. (d-f) Signal molecules involved in the inflammation-related pathways were detected with western blot. The results were presented as the mean ± SD, ^∗p < 0.05, ^∗∗p < 0.01 vs. the NS group.