Fig. 4. Intercalation and insertion. (A) Δ-α-[Rh{(R,R)-Me2trien}phi]3+ intercalated into 5′-G(5|U)TGCAAC-3′ with additional stabilisation by H-bonds from the ancillary ligand (PDB ; 454d), black lines indicate hydrogen bonds and (B) Δ-[Rh(bpy)2(chrysi)]3+ inserted into (5′-CGGAAATTCCCG-3′), displacing a mismatched AC pair shown in green (PDB ; 2O1I) b; (C) intercalation of Λ-[Ru(phen)2(dppz)]2+ into d(CCGGTACCGG)2 (PDB ; 3U38); (D) Λ-[Ru(TAP)2(dppz)]2+ bound to d(CCGGATCCGG)2 by semi-intercalation (PDB ; 4YMC); TriplatinNC bound to Dickerson–Drew dodecamer (B-DNA) through backbone tracking (E) and groove spanning (F) interactions. (N–H···O P hydrogen bonds shown as dashed red lines); and (G) three-way DNA junction recognition by a metallosupramolecular helicate (Fe2L3)4+ where L = C25H20N4 (PDB ; 2ET0).
