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. 2019 Apr 17;170(2):330–344. doi: 10.1093/toxsci/kfz096

Figure 1.

Figure 1.

Schematic illustrating the DFP exposure paradigm and experimental design of imaging studies, adapted from (Hobson et al., 2017). Imaging and histopathological examinations were performed on 27 DFP-exposed and 5 VEH control rats at varying days postexposure (DPE). The number of DFP-injected animals (DFP) and VEH controls imaged per time point is listed at the end of each row. Asterisks at the day 3 imaging time point denote a technical error during image acquisition that resulted in dramatically reduced SUV values in 6 animals (Supplementary Figure 1). These scans were excluded during temporal modeling analysis. Note that subsets of animals were imaged at 1–7 days prior to DFP exposure (baseline).