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. 2019 Apr 17;170(2):330–344. doi: 10.1093/toxsci/kfz096

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Figure 6. — The extent of neuroinflammation detected by [¹⁸F]PBR111 PET is highly correlated with seizure severity. A, Parametric images of SUVR from DFP-intoxicated animals with low versus high SS_AVR over the first 4 h postexposure. White arrows indicate differential [¹⁸F]PBR111 uptake in the thalamus (arrow facing right) and the piriform cortex (arrow facing left). B, Scatter plot depicting the high positive correlation between SS_AVR and SUVR in the thalamus (r_s = 0.84; p < .001) and piriform cortex (r_s = 0.48; p < .01). DFP-intoxicated animals are indicated with black circles, while VEH control animals are indicated as black triangles.