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Estimates for the Ebolavirus Data Set with Changing Selection Pressure (ω).
| Homogenous ω | Time-Dependent ω | |
|---|---|---|
| ln MLE | −66,035 | −65,767 |
| Selection parameter(s) | ω = 0.028 (0.026; 0.030) | Intercept β0 = −0.559 (−0.822; −0.305) |
| Slope β1 = −0.417 (−0.449; −0.385) | ||
| Clock rate (subst./site/yr) | 0.0004 (0.0002; 0.0006) | 0.0002 (0.0001; 0.0003) |
| TMRCA (years) | 11,166 (7,894; 15,190) | 49,022 (30,586; 77,863) |
Note.—The time-dependent ω model resulted in a better fit compared with the homogenous ω model.
