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Survival curves of C57BL/6J mice systemically infected with wild-type or HU-evolved Candida albicans strains harboring either ChrRx3 or Chr2x3, with or without CSP treatment. CSP was administered intraperitoneally at a dose of 0.063 mg/kg body weight daily for 7 days, beginning 1 day after infection. Control mice were administered 100 μl of phosphate buffered saline intraperitoneally. Survival curves were compared using the log-rank test.
