Table 3. Deregulated gene expression in PBMCs of patients (n = 5) undergoing elective hip arthroplasty receiving regional anaesthesia (RA), immediately after operation (T1) and on the third postoperative day (T2).
| Genes | T1 | T2 | ||
|---|---|---|---|---|
| FC | p-value | FC | p-value | |
| CDKN1A | -3.8 | 0.029 | -2.9 | 0.015 |
| GADD45A | 22.2 | 0.06 | 8.5 | 0.530 |
| HSPB1 | 2.2 | 0.107 | 3.9 | 0.026 |
| IL1B | -2.2 | 0.022 | -2.1 | 0.025 |
| MT2A | 1.8 | 0.093 | 2.0 | 0.043 |
| PRDX1 | 9.2 | 0.047 | 1.8 | 0.783 |
| SOD2 | -7.2 | 0.060 | -2.4 | 0.140 |
| UGT1A4 | -1.8 | 0.032 | -1.8 | 0.034 |
The genes were expressed as Fold-change (FC) respect to time (T0). The significant down- and up-regulated genes are highlighted in bold.