Table 1. Patient demographics.
| N = 287 | |||
|---|---|---|---|
| Demographic | Case Subjects (n = 72) | Control Subjects (n = 215) | p-value |
| Sex, No. (%) | 0.99 | ||
| Female | 12 (16.7) | 36 (16.7) | |
| Male | 60 (83.3) | 179 (83.3) | |
| Age, y | 0.83 | ||
| Mean (SD) | 63.8 (9) | 63.6 (8.8) | |
| Pack-years of smoking | 0.64 | ||
| Mean (SD) | 53.0 (25) | 51.5 (22.9) | |
| Smoking status, No. (%) | 0.0014 | ||
| Active smokers | 53 (73.6%) | 112 (52.1%) | |
| BMI | 0.46 | ||
| Mean (SD) | 26.7 (4.7) | 27.2 (3.9) | |
| Airflow obstruction, No. (%) | |||
| None | 33 (45.8) | 150 (69.8) | 0.0004 |
| GOLD I | 27 (37.5) | 36 (16.3) | |
| GOLD II | 9 (12.5) | 27 (12.6) | |
| GOLD III-IV | 3 (4.2) | 3 (1.4) | |
| Emphysema, No. (%) | 59 (81.9) | 90 (41.8) | <0.001 |
| CLE, No. (%) | 30 (50.8) | 9 (10) | <0.001 |
| PSE, No. (%) | 2 (3.4) | 31 (34.4) | |
| CLE and PSE, No. (%) | 27 (45.8) | 50 (55.5) | |
Definition of abbreviations: SD = Standard deviation; BMI = body mass index; GOLD = Global Initiative for Chronic Obstructive Lung Disease; CLE = Centrilobular; PSE = Paraseptal.