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. 2019 Jul 25;14(7):e0219766. doi: 10.1371/journal.pone.0219766

Table 3. Gender-stratified frequencies of malignancies and standard incidence ratios (SIR) for China, 2008 to 2011.

Malignancy Site/Type (ICD-O-3 Code) Males Females
Observed Expecteda SIRa (CI) Observed Expecteda SIRa (CI)
All Cancers 2,808 832.2 3.4 (3.3–3.5) 1,011 392.6 2.6 (2.4–2.7)
    All (Excluding Ill-defined/Unspecified) 2,524 809.9 3.1 (3.0–3.2) 898 382.2 2.3 (2.2–2.5)
    Ill–defined/Unspecified 284 22.3 12.8 (11.3–14.3) 113 10.4 10.9 (9.0–13.1)
AIDS-Defining Cancers (all lymphomasb) 431 21.6 19.9 (18.1–21.9) 284 40.7 7.0 (6.2–7.8)
    Kaposi sarcoma (9140) 132 0.05 2,639.8 (2,208.7–3,130.5) 39 0.02 1,593.5 (1,133.0–2,178.4)
    Lymphomab (959, 965) 299 21.6 13.9 (12.3–15.5) 117 7.3 16.0 (13.2–19.1)
    Cervical (C53) - - - 128 33.4 3.8 (3.2–4.6)
Non-AIDS-Defining Cancers (no lymphomasb) 2,377 810.6 2.9 (2.8–3.1) 727 351.9 2.1 (1.9–2.2)
    Oral cavity (C00–C09) 13 9.9 1.3 (0.7–2.2) 4 3.3 1.2 (0.3–3.1)
    Nasopharynx (C11) 38 22.9 1.7 (1.2–2.3) 9 5.2 1.7 (0.8–3.3)
    Other head and neck (C12–C14, C30–C32) 47 13.6 3.4 (2.5–4.6) 17 1.1 16.0 (9.3–25.6)
    Esophagus (C15) 78 62.5 1.2 (1.0–1.6) 19 10.9 1.7 (1.0–2.7)
    Stomach (C16) 137 116.1 1.2 (1.0–1.4) 60 26.7 2.2 (1.7–2.9)
    Colon and rectum (C18–C20) 121 81.5 1.5 (1.2–1.8) 32 29.5 1.1 (0.7–1.5)
    Anus (C21) 2 0.7 2.9 (0.3–10.5) 0 0.2 0.0 (0.0–19.7)
    Liver (C22) 539 138.3 3.9 (3.6–4.2) 84 16.1 5.2 (4.2–6.5)
    Other digestive system (C23, C24, C26) 6 12.1 0.5 (0.2–1.1) 1 5.3 0.2 (0.0–1.0)
    Pancreas (C25) 41 19.7 2.1 (1.5–2.8) 2 6.1 0.3 (0.0–1.2)
    Lung (C34) 713 150.1 4.8 (4.4–5.1) 140 33.2 4.2 (3.5–5.0)
    Mediastinum and pleura (C38) 4 4.9 0.8 (0.2–2.1) 2 1.3 1.5 (0.2–5.5)
    Bone (C40) 11 7.0 1.6 (0.8–2.8) 2 2.5 0.8 (0.1–2.8)
    Skin (C44) 17 7.5 2.3 (1.3–3.6) 9 2.2 4.0 (1.8–7.7)
    Soft tissue (C47–C49) 5 4.5 1.1 (0.4–2.6) 7 1.8 3.9 (1.5–8.0)
    Breast (C50) 2 1.2 1.6 (0.2–5.8) 31 98.8 0.3 (0.2–0.4)
    Vagina and vulva (C51, C52) - - - 2 0.9 2.2 (0.2–8.0)
    Corpus uteri (C54) - - - 48 17.4 2.8 (2.0–3.7)
    Ovary and other female genital tissue (C55–C58) - - - 5 18.0 0.3 (0.1–0.6)
    Penis (C60) 6 2.2 2.8 (1.0–6.1) - - -
    Prostate (C61) 9 14.8 0.6 (0.3–1.2) - - -
    Other male genital tissue (C62, C63) 5 5.0 1.0 (0.3–2.4) - - -
    Kidney (C64) 10 20.6 0.5 (0.2–0.9) 2 5.2 0.4 (0.0–1.4)
    Other urinary system (C65–C68) 3 2.7 1.1 (0.2–3.3) 0 1.0 0.0 (0.0–3.5)
    Bladder (C67) 9 24.0 0.4 (0.2–0.7) 1 2.9 0.4 (0.0–1.9)
    Eye (C69) 4 0.4 10.3 (2.8–26.4) 3 0.3 9.6 (1.9–28.1)
    Brain and CNS (C70, C71) 216 26.4 8.2 (7.1–9.3) 105 11.9 8.8 (7.2–10.7)
    Thyroid (C73) 2 17.3 0.1 (0.0–0.4) 0 28.8 0.0 (0.0–0.1)
    Multiple myeloma (C90) 4 3.8 1.1 (0.3–2.7) 1 1.3 0.8 (0.0–4.3)
    Melanoma (872) 1 1.6 0.6 (0.0–3.6) 0 0.7 0.0 (0.0–5.2)
    Leukemia (981) 50 17.2 2.9 (2.2–3.8) 28 8.8 3.2 (2.1–4.6)

ICD-O-3: International Classification of Disease for Oncology [32], 3rd Edition, SIR: standard incidence ratio, CI: 95% confidence interval, CNS: central nervous system

aSIR is calculated using Chinese National Cancer Registry data for 2008 (Expected) [35], and CI calculated based on an assumed Poisson distribution

bBecause approximately half of lymphoma records did not specify Hodgkin or Non-Hodgkin lymphoma, combined observed and expected lymphoma figures were calculated