Figure 2.

Transient receptor potential ankyrin 1 (TRPA1) mRNA levels in the antral mucosa correlates with abdominal symptoms after cold water intake in diarrhea-predominant irritable bowel syndrome (IBS-D) patients. Abdominal symptom scores before and after warm (A) and cold (4°C; B) water intake in heathy controls and IBS-D patients. **P < 0.01 (Paired Student’s t test). (C) Correlation between antral TRPA1 mRNA levels and abdominal symptom scores after intake of cold water in IBS-D patients. HC, healthy controls.