Table 2.
Individual risk of bias and quality assessment using SYRCLE (Systematic Review Centre for Laboratory Animal Experimentation)
| Study | Selection | Performance | Detection | Attrition | Reporting | ||||
|---|---|---|---|---|---|---|---|---|---|
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| Sequence generation | Baseline characteristics | Allocation concealment | Random housing | Performance blinding | Random outcome assessment | Blinding of outcome assessment | Incomplete outcome data | Selective outcome reporting | |
| Albersen 2010 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Unclear | Unclear |
| Lin 2011 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Low risk of bias | Unclear |
| Fandel 2012 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Low risk of bias | Unclear |
| Piao 2012 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Low risk of bias | High risk of bias | Unclear |
| Jeong 2013 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Low risk of bias | Low risk of bias | Unclear |
| Kim 2013 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Low risk of bias | Unclear | Unclear |
| Ying 2013 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Low risk of bias | Unclear |
| You 2014 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Low risk of bias | Low risk of bias | Low risk of bias | Unclear |
| Bae 2013 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Low risk of bias | Unclear |
| Lee 2014 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Low risk of bias | Unclear |
| Ying 2014 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Unclear | Unclear |
| Xu 2014 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Low risk of bias | Unclear |
| Yang 2015 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Low risk of bias | Unclear |
| You 2015 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Low risk of bias | Low risk of bias | Low risk of bias | Unclear |
| Chen 2015 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Low risk of bias | Unclear |
| Jeon 2015 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Unclear | Unclear |
| Lin 2016 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Low risk of bias | Unclear |
| Wu 2018 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Unclear | Unclear |
| Zheng 2018 | Unclear | Low risk of bias | Unclear | Unclear | Unclear | Unclear | Unclear | Low risk of bias | Unclear |