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. 2019 Apr 30;12(2):291–303. doi: 10.15283/ijsc19002

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Copyright © 2019 by the Korean Society for Stem Cell Research

This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Fig. 4 — Intracellular signaling induced by H-CM in HeLa cells. Upregulated proteins (red) involved in intracellular signaling of HeLa cells treated with H-CM compared with N-CM according to protein antibody array (>1.5 fold) (A). Biological process of GO analysis for upregulated intracellular proteins in HeLa cells treated with H-CM compared with N-CM (B). KEGG pathway analysis of upregulated intracellular proteins in HeLa cells treated with H-CM compared with N-CM (C). Downregulated proteins (green) involved in intracellular signaling of HeLa cells treated with H-CM compared with N-CM according to protein antibody array (>1.5 fold) (D). Biological process of GO analysis for downregulated intracellular proteins in HeLa cells treated with H-CM compared with N-CM (E). KEGG pathway analysis of downregulated intracellular proteins in HeLa cells treated with H-CM compared with N-CM (F). GO and KEGG pathway results were represented as the –log₁₀ p value (p<0.01) and top 10 enriched terms, and single sample analysis was performed.