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. 2019 Jun 20;44(3):995–1005. doi: 10.3892/ijmm.2019.4250

Figure 3.

Figure 3

SIRT1 expression levels in HBMECs modulate endothelial-monocyte interactions. (A) Representative images showing adherence of fluorescent THP-1 cells to endothelial monolayers at different treatment condition. (B) Quantification of calcein AM labelled THP-1 cells that adhere to HBMECs at different conditions with or without TNF-α (10 ng/ml) treatment. Data are presented as the mean ± standard deviation of three different experiments. *P<0.05 and **P<0.01 vs. NT control group. #P<0.05. Scale bar: 10 µm. HBMECs, human brain microvascular endothelial cells; TNF, tumor necrosis factor; si, small interfering; SIRT1, sirtuin1.