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. 2019 Jul 3;44(3):1048–1062. doi: 10.3892/ijmm.2019.4264

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Copyright: © Yao et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Hydrogen improves cardiac dysfunction in rats induced by myocardial I/R. Myocardial injury and hydrogen treatment was performed as outlined in Fig. 1. (A) -dp/dt_max, (B) +dp/dt_max, (C) LVEF and (D) LVEDP were measured. Values are presented as mean ± standard error of the mean (n=6 rats per group). ^*P<0.05 vs. control group; and ^#P<0.05 vs. I/R group. I/R, ischemia/reperfusion; -dp/dt_max, maximal rate of the decrease of left ventricular pressure; +dp/dt_max, maximal rate of the increase of left ventricular pressure; LVEF, left ventricular ejection fraction; LVEDP, left ventricular ejection fraction; Con, control.