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. 2019 Jun 20;44(3):813–822. doi: 10.3892/ijmm.2019.4248

Figure 4.

Figure 4

GL inhibits HMGB1 transport and the expression of RAGE following recanalization. (A) Immunofluorescent staining showing differences in the extracellular and intracellular distribution of HMGB1 in paranasal sinus brain tissues. Magnification, ×200. (B) Quantification of HMGB1 fluorescence intensity. (C) Immunofluorescent staining showing changes in the expression of RAGE in paranasal sinus brain tissues. Magnification, ×200. (D) Quantification of RAGE fluorescence intensity. ***P<0.001. GL, glycyrrhizin; NS, normal saline; HMGB1, high-mobility group box 1; RAGE, receptor of advanced glycation end products.