Table 1.

Patient characteristics and outcomes according to embryonal tumor type.

	n	NBL n = 101	WT n = 67	RMS n = 10	HBL n = 23	Combined n = 201	P value
Age at diagnosis (months)	201	21 [8, 51]	42 [20, 53]	30.5 [19, 64]	18 [7, 25]	28 [12, 51]	< .001
Sex
Male	201	52% (52)	36% (24)	50% (5)	577% (13)	47% (94)	.168
Female		49% (49)	64% (43)	50% (5)	44% (10)	53% (107)
Race
White, non-Hispanic	201	77% (78)	69% (46)	90% (9)	74% (17)	75% (150)	.708
White, Hispanic		3% (3)	8% (5)	10% (1)	(1)	5% (10)
Black		13% (13)	16% (11)	(0)	(3)	13% (27)
Asian		3% (3)	(0)	(0)	(1)	(4)
Other		4% (4)	8% (5)	(0)	(1)	5% (10)
Tumor volume
Diagnosis (mL)	200	140.1 [30.5, 326.2]	503.4 [240, 746]	59.2 [30.2, 289.3]	252.2 [133.9, 532]	215.0 [42.9, 546.0]	< .001
Resection (mL)*	174	40.1 [11.3, 124.8]	438.0 [115.2, 705.8]	18.9 [4.5, 29.1]	43.1 [34.6, 153.8]	84.0 [20.4, 372.5]	< .001
Timing of resection*
Upfront	174	48% (40)	82% (54)	(1)	56% (10)	60% (105)	< .001
After neoadjuvant		52% (44)	18% (12)	83% (5)	44% (8)	40% (69)
Resection approach
Open TV >100 mL	201	23% (23)	75% (50)	(1)	35% (8)	41% (82)	< .001
Open TV <100 mL		41% (41)	21% (14)	30% (3)	44% (10)	34% (68)
MIS		20% (20)	(2)	20% (2)	(0)	12% (24)
No resection		17% (17)	(1)	40% (4)	22% (5)	13% (27)
Margin status*
Negative	158	36% (25)	77% (50)	40% (2)	94% (17)	60% (94)	< .001
Positive		64% (45)	23% (15)	60% (3)	(1)	41% (64)
Relapse at 5 years
No	108	67% (37)	83% (30)	86% (6)	100% (10)	77% (83)	.072
Yes		33% (18)	17% (6)	(1)	(0)	23% (25)
Survival at 5 years
Alive	117	70% (41)	94% (34)	75% (6)	72% (10)	78% (91)	.037
Dead		31% (18)	(2)	25% (2)	29% (4)	22% (26)

NBL, neuroblastoma; WT, Wilms tumor; RMS, rhabdomyosarcoma; HBL, hepatoblastoma; TV, tumor volume.

^*Includes resected tumors only (84 NBL, 66 WT, 6 RMS, 18 HBL).