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. Author manuscript; available in PMC: 2019 Dec 7.
Published in final edited form as: J Mol Biol. 2018 Oct 28;430(24):5029–5049. doi: 10.1016/j.jmb.2018.10.015

Figure 8: ITC of phosphorylation effect on stability of kinase/channel fragment complex.

Figure 8:

a) Titration of dEAGshort into the partially inactive form of CaMKII kinase domain mutant D136N in the presence of Mg2+-AMPPNP. b) Titration of dEAGshortP into CaMKII kinase domain mutant D136N in the presence of Mg2+-ADP. c) Titration of dEAGshort into CaMKII kinase domain mutant D136N in the presence of Mg2+-ADP. Titration injection heats are shown in the upper panel and binding isotherm of integrated binding enthalpies in the lower panel. KD values are shown for each mutant in lower panels.